Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | BHMT | Q93088 | 3/20 | 0.43 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 3/20 | 0.39 |
| ▸ | ARG2 | P78540 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL8836635 | 1.00 | GSR (0.59) | GSRSLC7A5SLC1A2SLC1A3BHMT | |
| Leucine SCHEMBL15324335 | 0.94 | SLC7A5 (0.53) | GSRSLC7A5SLC1A2SLC1A3BHMT | |
| Leucine SCHEMBL15324338 | 0.94 | SLC7A5 (0.53) | GSRSLC7A5SLC1A2SLC1A3BHMT | |
| Lysine SCHEMBL8860269 | 0.92 | GSR (0.50) | GSRSLC7A5SLC1A2SLC1A3BHMT | |
| Lysine SCHEMBL8860263 | 0.92 | GSR (0.50) | GSRSLC7A5SLC1A2SLC1A3BHMT | |
| Lysine SCHEMBL10491088 | 0.91 | GSR (0.71) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL938951 | 0.91 | GSR (0.71) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL8720001 | 0.91 | GSR (0.71) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL1345091 | 0.91 | GSR (0.71) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL1345092 | 0.91 | GSR (0.71) | GSRBHMTBHMT2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1819825-A | Amino acid iodine composition and preparation method and application thereof | ZENG XIONGFEI (CN) | 2006-08-16 | — | — | CN | claimed |
| CN-1087139-C | Breeding and raising method of meat qinglong dog | ZHANG CHUNHUA (CN) | 2002-07-10 | — | — | CN | disclosed |
| EP-0806938-A1 | CARRIER PARTICLES FOR USE IN DRY POWDER INHALERS | CO-ORDINATED DRUG DEVELOPMENT LIMITED (GB) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023485-A1 | CARRIER PARTICLES FOR USE IN DRY POWDER INHALERS | CO-ORDINATED DRUG DEVELOPMENT LIMITED (GB) | 1996-08-08 | — | — | WO | disclosed |