Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.36 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158949 | 0.79 | — | — | |
| SCHEMBL30158804 | 0.79 | — | — | |
| SCHEMBL29187940 | 0.79 | — | — | |
| SCHEMBL29187938 | 0.79 | — | — | |
| SCHEMBL27477105 | 0.74 | PEPD (0.41) | GABRR1GABRR2 | |
| SCHEMBL7739490 | 0.74 | PEPD (0.37) | GABRR1GABRR2 | |
| SCHEMBL17082724 | 0.73 | HSD11B1 (0.32) | — | |
| SCHEMBL9173498 | 0.71 | PLG (0.36) | GABRR1GABRR2 | |
| SCHEMBL19927749 | 0.68 | SLC1A2 (0.36) | GABRR1GABRR2 | |
| SCHEMBL24850110 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641784-A | ADENOSINE ANTAGONISTS; TREATMENT OF NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM KG (DE) | 1997-06-24 | — | — | US | disclosed |