Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 8/20 | 0.45 |
| ▸ | TACR1 | P25103 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477810 | 1.00 | GPR183 (0.45) | GPR183TACR1KCNH2HRH3MAOA | |
| SCHEMBL9239257 | 1.00 | GPR183 (0.45) | GPR183TACR1KCNH2HRH3MAOA | |
| SCHEMBL8478659 | 0.95 | L3MBTL1 (0.42) | GPR183TACR1 | |
| SCHEMBL8478660 | 0.95 | L3MBTL1 (0.42) | GPR183TACR1 | |
| SCHEMBL9236774 | 0.95 | L3MBTL1 (0.42) | GPR183TACR1 | |
| SCHEMBL9236781 | 0.95 | L3MBTL1 (0.42) | GPR183TACR1 | |
| SCHEMBL8480591 | 0.94 | RHOC (0.44) | GPR183TACR1 | |
| SCHEMBL9238971 | 0.94 | RHOC (0.44) | GPR183TACR1 | |
| SCHEMBL9238976 | 0.94 | RHOC (0.44) | GPR183TACR1 | |
| SCHEMBL8480595 | 0.94 | RHOC (0.44) | GPR183TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655442-A1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |