Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 5/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.34 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.32 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.32 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.32 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326961 | 1.00 | CHRM5 (0.37) | CHRM5LIPGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL7326295 | 0.95 | FDFT1 (0.33) | CHRM5LIPGHRH3FAAHMGLL | |
| SCHEMBL7324293 | 0.95 | FDFT1 (0.33) | CHRM5LIPGHRH3FAAHMGLL | |
| SCHEMBL7327618 | 0.92 | CHRM5 (0.36) | CHRM5ITGB3ITGA2BPTGDR2 | |
| SCHEMBL7321624 | 0.92 | CHRM5 (0.36) | CHRM5ITGB3ITGA2BPTGDR2 | |
| SCHEMBL9285955 | 0.91 | CTRB1 (0.36) | LIPGITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL8836959 | 0.91 | CHRM5 (0.39) | CHRM5LIPGPLAAT3PLAAT5PLAAT2 | |
| Trifluoroacetic Acid SCHEMBL7326956 | 0.91 | CHRM5 (0.39) | CHRM5LIPGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8836947 | 0.90 | ALDH1A1 (0.37) | CHRM5HRH3ITGB3ITGA2BPTGDR2 | |
| SCHEMBL7320353 | 0.90 | ALDH1A1 (0.37) | CHRM5HRH3ITGB3ITGA2BPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674863-A | BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR | GENENTECH, INC. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5674865-A | BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR | GENENTECH, INC. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5403836-A | Anticoagulants | GENENTECH, INC. (US) | 1995-04-04 | — | — | US | disclosed |
| US-5250679-A | Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor | GENENTECH, INC. (US) | 1993-10-05 | — | — | US | disclosed |