Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.38 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448563 | 0.88 | AGTR1 (0.44) | CRHR1AGTR1AGTR2 | |
| SCHEMBL7443465 | 0.78 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7437565 | 0.76 | MAPT (0.38) | UBE2MDCUN1D1AGTR1AGTR2 | |
| SCHEMBL7439284 | 0.75 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7431258 | 0.75 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL7438702 | 0.75 | DPP4 (0.42) | UBE2MDCUN1D1 | |
| SCHEMBL7442522 | 0.75 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7440067 | 0.75 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7442873 | 0.73 | CMKLR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7438261 | 0.72 | DPP4 (0.34) | CRHR1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602136-A | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1997-02-11 | — | — | US | disclosed |