Diphenylether

Diphenylether

SCHEMBL8837235

OCCO.OCCO.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.71
TSHR P16473 1/20 0.71
NR1H2 P55055 1/20 0.59
BAX Q07812 1/20 0.59
ALDH1A1 P00352 1/20 0.56
RECQL P46063 1/20 0.56
MAOA P21397 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
GAA P10253 1/20 0.48
KMT2A Q03164 1/20 0.48
FFAR1 O14842 1/20 0.48
GSTP1 P09211 1/20 0.48
PARP10 Q53GL7 1/20 0.48
PLA2G2A P14555 1/20 0.48
SRD5A2 P31213 1/20 0.47
TTR P02766 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL51188 1.00 LTA4H (0.71) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL12970954 0.95 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL4624646 0.95 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL11414038 0.95 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL27801863 0.95 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL4623522 0.95 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL22634177 0.95 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL4623898 0.95 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL1373717 0.89 LTA4H (0.63) LTA4HTSHRNR1H2BAXALDH1A1
Diphenylether SCHEMBL896890 0.88 LTA4H (0.55) LTA4HTSHRNR1H2BAXALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5599474-A SILICON OIL CARRIER FLUID, MAGNETORHEOLOGICAL PARTICLES LORD CORPORATION (US) 1997-02-04 US disclosed