Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Diphenylether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL29175285 | 0.91 | LTA4H (0.67) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL1830446 | 0.91 | LTA4H (0.67) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL8671677 | 0.88 | LTA4H (0.63) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL27801863 | 0.88 | LTA4H (0.63) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL51188 | 0.88 | LTA4H (0.71) | LTA4HTSHRFFAR1PARP10SRD5A2 | |
| Diphenylether SCHEMBL8837235 | 0.88 | LTA4H (0.71) | LTA4HTSHRFFAR1PARP10SRD5A2 | |
| Diphenylether SCHEMBL55934 | 0.88 | LTA4H (0.47) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL6560478 | 0.87 | FFAR1 (0.52) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL19064985 | 0.86 | ALDH1A1 (0.48) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL29116059 | 0.86 | LTA4H (0.60) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119028631-A | Organic carrier for solar cell conductive paste, preparation method and application | 杭州正银电子材料有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-116646111-B | Conductive silver-aluminum paste and preparation method and application thereof | 无锡帝科电子材料股份有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-115083659-B | Conductive paste for laser transfer printing, preparation method and application thereof | 常州聚和新材料股份有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-118675789-A | Slurry for TOPCon battery back fine grid printing and preparation method thereof | 常州聚和新材料股份有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118652064-A | Method for preparing high-performance admixture by exciting carbonization activity of steel slag by using additive | 南京工业大学 | 2024-09-17 | — | — | CN | claimed |
| CN-113963840-B | Low-temperature conductive paste composition and preparation method and application thereof | 无锡帝科电子材料股份有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118406404-A | Circuit board ink-jet printing ink stripping agent and preparation method and application thereof | 珠海市板明科技有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118299100-A | Glass powder composition, back silver paste and IBC solar cell | 苏州晶银新材料科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-117903624-A | Organic carrier for conductive silver paste and preparation method and application thereof | 杭州正银电子材料有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117153457-B | Conductive paste for preparing conductive grid line, organic carrier and application thereof | 常州聚和新材料股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-104140604-A | Halogen-free flame retardant PVC (polyvinyl chloride) material for automobiles and preparation method of halogen-free flame retardant PVC material | LU AN XIECHENG VEHICLE PARTS CO LTD | 2014-11-12 | — | — | CN | claimed |
| CN-103664590-A | Method for synthesizing compound containing 4-(2-hydroxy ethoxy) diphenylketone structure or acetate thereof | SYNYOO NEW MATERIALS CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-103214907-A | Aqueous microwave absorbing anticorrosion protection paint and preparation method thereof | UNIV HUBEI | 2013-07-24 | — | — | CN | claimed |
| CN-103219065-A | Carbon nanotube-nanometer copper powder-based environment-friendly conductive paste | UNIV TIANJIN TECHNOLOGY | 2013-07-24 | — | — | CN | claimed |
| CN-103193957-A | Waterborne polyurethane, waterborne antistatic coating composition and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY | 2013-07-10 | — | — | CN | claimed |
| CN-102146247-A | Waterproof coating containing polyether-modified silicon-acrylic soft resin and preparation method thereof | WUHAN XINKANG CHEMICAL CORP CO LTD | 2011-08-10 | — | — | CN | claimed |
| CN-101811951-A | Preparation method of 2-hydroxyl-1-{4-(2-hydroxyethyl) phenyl}-2-methyl-1-acetone | GANSU JINDUN CHEMICAL CO LTD | 2010-08-25 | — | — | CN | claimed |
| CN-101703869-A | New method and device for recovering organic solvent from waste gas | MA JUN | 2010-05-12 | — | — | CN | claimed |
| CN-101081025-A | Application of SC2053 in the emasculation of rescue brome and reed shaped sheep fescuesheep and the emasculation method thereof | GUIZHOU FARMING ANIMAL SCIENCE (CN) | 2007-12-05 | — | — | CN | claimed |
| US-5700860-A | Liquid crystal orienting agent | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1997-12-23 | — | — | US | claimed |