Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849328 | 0.84 | MLYCD (0.41) | HDAC1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL31248355 | 0.84 | PRSS1 (0.52) | LMNAGAACA12CA1CA7 | |
| SCHEMBL5435586 | 0.83 | MEN1 (0.44) | HDAC1HDAC6L3MBTL1KMT2AMEN1 | |
| SCHEMBL31248371 | 0.82 | HDAC1 (0.52) | HDAC1HDAC6GAAKMT2AALDH1A1 | |
| SCHEMBL30596225 | 0.81 | KMT2A (0.49) | POLBGAAKMT2AHPGDMEN1 | |
| SCHEMBL6295798 | 0.80 | MLYCD (0.48) | KMT2AMEN1ALDH1A1GLA | |
| SCHEMBL464919 | 0.80 | HDAC1 (0.57) | HDAC1HDAC6LMNAL3MBTL1GAA | |
| SCHEMBL4793278 | 0.80 | HDAC1 (0.60) | HDAC1HDAC6LMNAL3MBTL1GAA | |
| SCHEMBL219603 | 0.80 | SMN1; SMN2 (0.49) | L3MBTL1KMT2AMEN1ALDH1A1GLA | |
| SCHEMBL17974957 | 0.79 | MEN1 (0.47) | L3MBTL1KMT2AMEN1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654301-A | Lacosamide FDA Orange book listed patent | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
| EP-0263506-A2 | Anticonvulsant composition containing amino acid derivative and use of said amino acid derivative | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-04-13 | — | — | EP | disclosed |