SCHEMBL8837482

SCHEMBL8837482

C=CCSC(C)(C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
TSHR P16473 3/20 0.32
TRPA1 O75762 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX5 P09917 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15973850 0.78 CYP2C19 (0.35) CYP2C19
SCHEMBL17419430 0.78 CYP2C19 (0.35) CYP2C19
SCHEMBL11498755 0.76 ALDH1A1 (0.37) ALDH1A1TSHRTRPA1CYP3A4HPGD
SCHEMBL27569759 0.75
Propionic Acid SCHEMBL11771893 0.75 FFAR3 (0.39) ALDH1A1TSHRTRPA1CYP3A4HPGD
SCHEMBL7591079 0.74 ALDH1A1 (0.33) ALDH1A1TSHRTRPA1CYP3A4HPGD
SCHEMBL4290498 0.74 PKM (0.38) ALDH1A1TSHRCYP3A4ALOX15SMN1; SMN2
SCHEMBL2362804 0.72 ALDH1A1 (0.39) ALDH1A1
SCHEMBL10967037 0.70
Bicarbonate SCHEMBL28903846 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5690904-A BRAIN IMAGING AGENTS AMERSHAM INTERNATIONAL PLC (GB) 1997-11-25 US disclosed