Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812702 | 0.82 | CA12 (0.78) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL6794824 | 0.79 | CA12 (0.73) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL3822617 | 0.79 | CA12 (1.00) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL18946200 | 0.78 | CA12 (0.55) | CA12CA9TSHRMAPTKMT2A | |
| SCHEMBL7822429 | 0.77 | CA12 (0.71) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL7811989 | 0.77 | CA12 (0.71) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL2518894 | 0.77 | CA12 (0.71) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL11174158 | 0.77 | CA12 (0.71) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL14469933 | 0.77 | FFAR1 (0.74) | CA12CA9TSHRNR1H3MAPT | |
| SCHEMBL11181741 | 0.77 | PGR (0.74) | CA12CA9TSHRNR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693639-A | TREATING URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1997-12-02 | — | — | US | disclosed |
| US-5510386-A | ADMINISTERING TO RELAX SMOOTH MUSCLE OF THE BLADDER | ZENECA LIMITED (GB) | 1996-04-23 | — | — | US | disclosed |