Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345524 | 0.76 | — | — | |
| SCHEMBL8778459 | 0.70 | FKBP5 (0.37) | — | |
| SCHEMBL12028362 | 0.68 | POLB (0.38) | POLBALDH1A1 | |
| SCHEMBL1688444 | 0.68 | FKBP5 (0.36) | — | |
| SCHEMBL8837747 | 0.67 | CRBN (0.43) | POLBALDH1A1 | |
| SCHEMBL1997375 | 0.67 | — | — | |
| SCHEMBL186373 | 0.66 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL23752900 | 0.64 | — | — | |
| SCHEMBL7164814 | 0.64 | CRBN (0.46) | POLBALDH1A1 | |
| SCHEMBL7171070 | 0.64 | CRBN (0.39) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654294-A | CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB (US) | 1997-08-05 | — | — | US | disclosed |
| US-5646276-A | ANGIOTENSIN CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE INHIBITORS; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5552397-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-09-03 | — | — | US | disclosed |