Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431892 | 1.00 | ACE (0.59) | ACEMME | |
| SCHEMBL7713390 | 0.79 | ACE (0.57) | ACEMME | |
| Gemopatrilat SCHEMBL1973289 | 0.75 | ACE (1.00) | ACEMME | |
| SCHEMBL7540477 | 0.72 | ACE (0.73) | ACEMME | |
| SCHEMBL7540483 | 0.72 | ACE (0.73) | ACEMME | |
| SCHEMBL3281359 | 0.71 | ACE (0.48) | ACE | |
| SCHEMBL7543963 | 0.71 | ACE (0.48) | ACE | |
| SCHEMBL8837762 | 0.70 | TRPA1 (0.33) | ACE | |
| SCHEMBL8428728 | 0.70 | TRPA1 (0.33) | ACE | |
| SCHEMBL14170611 | 0.69 | ACE (0.47) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654294-A | CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB (US) | 1997-08-05 | — | — | US | disclosed |
| US-5646276-A | ANGIOTENSIN CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE INHIBITORS; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5552397-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-09-03 | — | — | US | disclosed |