Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540483 | 1.00 | ACE (0.73) | ACEMME | |
| SCHEMBL8837721 | 0.91 | ACE (0.60) | ACEMME | |
| SCHEMBL8837709 | 0.91 | ACE (0.60) | ACEMME | |
| SCHEMBL8837711 | 0.91 | ACE (0.60) | ACEMME | |
| SCHEMBL8837731 | 0.91 | ACE (0.60) | ACEMME | |
| Gemopatrilat SCHEMBL5213866 | 0.85 | ACE (1.00) | ACEMME | |
| Gemopatrilat SCHEMBL1973289 | 0.85 | ACE (1.00) | ACEMME | |
| Gemopatrilat SCHEMBL13575789 | 0.85 | ACE (1.00) | ACEMME | |
| SCHEMBL8485277 | 0.81 | ACE (0.56) | ACEMME | |
| SCHEMBL8430427 | 0.80 | ACE (0.49) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444810-B1 | ACYLMERCAPTOALKANOYLAMINO LACTAM ESTERS OR ACIDS ARE CONVERTED TO THE CORRESPONDING MERCAPTOALKANOYLAMINO LACTAM ESTER OR ACID UNDER BASIC CONDITIONS USING AN AGENT THAT MINIMIZES AMOUNT OF DISULFIDES | BRISTOL-MYERS SQUIBB CO. | 2002-09-03 | — | — | US | claimed |
| EP-1051419-A4 | DEPROTECTION AND RECRYSTALLIZATION PROCESSES | BRISTOL MYERS SQUIBB CO (US) | 2002-08-28 | — | — | EP | claimed |
| US-20020086994-A1 | Acylmercaptoalkanoylamino lactam esters or acids are converted to the corresponding mercaptoalkanoylamino lactam ester or acid under basic conditions using an agent that minimizes amount of disulfides | KRONENTHAL DAVID R (US) | 2002-07-04 | — | — | US | claimed |
| EP-1051419-A1 | DEPROTECTION AND RECRYSTALLIZATION PROCESSES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-11-15 | — | — | EP | claimed |
| WO-1999035145-A1 | DEPROTECTION AND RECRYSTALLIZATION PROCESSES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-07-15 | — | — | WO | claimed |
| US-6486315-B2 | RECRYSTALLIZING MERCAPTOALKANOYLAMINO LACTAM ACID UNDER BASIC CONDITIONS USING AN AGENT THAT MINIMIZES AMOUNT OF DISULFIDES | BRISTOL-MYERS SQUIBB CO. | 2002-11-26 | — | — | US | disclosed |
| US-6444810-B1 | ACYLMERCAPTOALKANOYLAMINO LACTAM ESTERS OR ACIDS ARE CONVERTED TO THE CORRESPONDING MERCAPTOALKANOYLAMINO LACTAM ESTER OR ACID UNDER BASIC CONDITIONS USING AN AGENT THAT MINIMIZES AMOUNT OF DISULFIDES | BRISTOL-MYERS SQUIBB CO. | 2002-09-03 | — | — | US | disclosed |
| US-20020086995-A1 | Recrystallization processes | KRONENTHAL DAVID R (US) | 2002-07-04 | — | — | US | disclosed |
| US-20020086994-A1 | Acylmercaptoalkanoylamino lactam esters or acids are converted to the corresponding mercaptoalkanoylamino lactam ester or acid under basic conditions using an agent that minimizes amount of disulfides | KRONENTHAL DAVID R (US) | 2002-07-04 | — | — | US | disclosed |
| US-6340752-B1 | CLEAVAGE OF THIO GROUP FROM CARBONYL AND CONVERSION TO LACTAM ESTER | BRISTOL-MYERS SQUIBB CO. | 2002-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086994-A1 | Acylmercaptoalkanoylamino lactam esters or acids are converted to the corresponding mercaptoalkanoylamino lactam ester or acid under basic conditions using an agent that minimizes amount of disulfides | MPST, PTMS, TST | ACE 315/4885MME 493/4885 |
| US-20020086995-A1 | Recrystallization processes | MPST, TST, SLC39A11 | ACE 1296/4885MME 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.