Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190098 | 0.88 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL883780 | 0.78 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL13190008 | 0.78 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL786085 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL785920 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL784976 | 0.69 | ALDH1A1 (0.49) | ALDH1A1BRD4CREBBPTAS1R3TAS1R1 | |
| SCHEMBL484844 | 0.69 | ALDH1A1 (0.49) | ALDH1A1BRD4CREBBPTAS1R3TAS1R1 | |
| SCHEMBL883818 | 0.69 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL784603 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HSD17B2BRD4CREBBPTAS1R3 | |
| SCHEMBL784602 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HSD17B2BRD4CREBBPTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |