SCHEMBL448516

SCHEMBL448516

CC=CCCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 12/20 0.55
ALDH1A1 P00352 2/20 0.45
MAOB P27338 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106847 1.00 GPR52 (0.55) GPR52ALDH1A1MAOBHPGDALOX15
SCHEMBL10479589 0.96 GPR52 (0.52) GPR52ALDH1A1MAOB
SCHEMBL10479586 0.96 GPR52 (0.52) GPR52ALDH1A1MAOB
SCHEMBL23168311 0.87 GPR52 (0.51) GPR52
SCHEMBL8838348 0.87 GPR52 (0.51) GPR52
SCHEMBL1225568 0.86 SIGMAR1 (0.50) MEN1KMT2A
SCHEMBL1225567 0.86 SIGMAR1 (0.50) MEN1KMT2A
SCHEMBL7762166 0.85 GPR52 (0.57) GPR52ALDH1A1MAOBHPGDALOX15
SCHEMBL9715286 0.85 GPR52 (0.57) GPR52ALDH1A1MAOBHPGDALOX15
SCHEMBL7762164 0.85 GPR52 (0.57) GPR52ALDH1A1MAOBHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773229-B 1,6 Diene compound and preparation method and application thereof 南京工业大学 2024-06-14 CN claimed
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
CN-1291977-C Polysubstituted quinazine derivative funcional material, and preparing method and thereof UNIV FUDAN (CN) 2006-12-27 CN claimed
CN-1528748-A Polysubstituted quinazine derivative funcional material, and preparing method and thereof 复旦大学 2004-09-15 CN claimed
US-4138411-A RUTHENIUM OR OSMIUM CATALYST RHONE-POULENC S. A. (FR) 1979-02-06 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
CN-114773229-B 1,6 Diene compound and preparation method and application thereof 南京工业大学 2024-06-14 CN disclosed
WO-2024099911-A1 IRON CARBONYL COMPLEXES WITH CHIRAL, BIDENTATE BIPHOSPHINE LIGANDS BASF SE (DE) 2024-05-16 WO disclosed
CN-117736096-A Preparation method of polysubstituted trifluoromethyl olefin compound 南京工业大学 2024-03-22 CN disclosed
US-4740647-A COPPER ALUMINUM BORATE TO CATALYZE DEHYDROCYCLIZATION OF ALKENYL AROMATIC COMPOUND AMOCO CORPORATION (US) 1988-04-26 US disclosed
US-4138411-A RUTHENIUM OR OSMIUM CATALYST RHONE-POULENC S. A. (FR) 1979-02-06 US disclosed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4062685-A ORGANO-TELLURIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JA) 1977-12-13 US disclosed
US-3997616-A FROM ALKENYLBENZENE, CYCLIZATION CATALYST TEIJIN LIMITED (JA) 1976-12-14 US disclosed
US-3989640-A SYNERGISTIC, MORPHOLINE, AMMONIUM BENZOATE AND CYCLOHEXANE OR NITROPROPANE OR CYCLOPENTENE THE DRACKETT COMPANY (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA GPR52 1379/4885ALDH1A1 753/4885MAOB 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.