Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL8838454 | 0.80 | KDM4E (0.37) | CCR1CCR5CCR8PLAUMAPT | |
| Tetramethylammonium Ion SCHEMBL8838505 | 0.76 | PLAU (0.34) | METPLAUALKS1PR1S1PR3 | |
| SCHEMBL18571994 | 0.76 | ALOX15 (0.36) | CCR1CCR5CCR8PLAUALK | |
| SCHEMBL22002092 | 0.75 | IDO1 (0.40) | CCR1CCR5CCR8SMN1; SMN2MAPT | |
| SCHEMBL557234 | 0.75 | CCR1 (0.52) | CCR1CCR5CCR8METALK | |
| SCHEMBL29407003 | 0.75 | CCR1 (0.52) | CCR1CCR5CCR8METALK | |
| SCHEMBL8838409 | 0.75 | CCR1 (0.67) | CCR1CCR5CCR8ALKPDE10A | |
| SCHEMBL27840289 | 0.74 | CCR1 (0.39) | CCR1CCR5CCR8PLAUALK | |
| SCHEMBL30505759 | 0.74 | CCR1 (0.39) | CCR1CCR5CCR8PLAUALK | |
| SCHEMBL8838388 | 0.74 | CCR1 (0.34) | CCR1CCR5CCR8ALKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625068-A | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0747361-A1 | Substituted quinoline herbicide intermediates and process | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |