Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066101 | 0.90 | PTGDR2 (0.45) | PTGDR2PTGDRCA5ACYP1A2 | |
| SCHEMBL2066559 | 0.90 | PTGDR2 (0.48) | PTGDR2PTGDRCA5ARORC | |
| SCHEMBL883879 | 0.88 | PTGDR2 (0.42) | PTGDR2PTGDRCA5ACYP1A2 | |
| SCHEMBL2066482 | 0.86 | PTGDR2 (0.49) | PTGDR2PTGDRCA5ARORC | |
| SCHEMBL2065425 | 0.86 | PTGDR2 (0.52) | PTGDR2PTGDRCA5ARORC | |
| SCHEMBL2065744 | 0.85 | CYP1A2 (0.43) | PTGDR2PTGDRCA5ACYP1A2 | |
| SCHEMBL883862 | 0.84 | PTGDR2 (0.47) | PTGDR2PTGDRRORC | |
| SCHEMBL2066732 | 0.81 | PTGDR2 (0.53) | PTGDR2PTGDR | |
| SCHEMBL586644 | 0.79 | PTGDR2 (0.48) | PTGDR2PTGDRCA5A | |
| SCHEMBL4639157 | 0.78 | PTGDR2 (0.47) | PTGDR2PTGDRCA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148572-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | claimed |
| US-20090192163-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | claimed |
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | claimed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | claimed |
| US-8148572-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | disclosed |
| US-8148572-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | disclosed |
| US-8148572-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | disclosed |
| US-20090192163-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| US-20090192163-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| US-20090192163-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192163-A1 | Novel Compounds | PAH, PC, DDC | PTGDR2 1000/4885PTGDR 859/4885CA5A 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.