SCHEMBL8838682

SCHEMBL8838682

CCCCCC(/C=C/I)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4975284 1.00 CA2 (0.32) CA2MEN1KMT2ACA1
SCHEMBL11491429 1.00 CA2 (0.32) CA2MEN1KMT2ACA1
SCHEMBL968053 1.00 CA2 (0.32) CA2MEN1KMT2ACA1
SCHEMBL968055 1.00 CA2 (0.32) CA2MEN1KMT2ACA1
SCHEMBL4975291 1.00 CA2 (0.32) CA2MEN1KMT2ACA1
SCHEMBL9547867 1.00 CA2 (0.32) CA2MEN1KMT2ACA1
SCHEMBL4975685 0.98 MEN1 (0.32) CA2MEN1KMT2A
SCHEMBL11405856 0.98 MEN1 (0.32) CA2MEN1KMT2A
SCHEMBL4975682 0.98 MEN1 (0.32) CA2MEN1KMT2A
SCHEMBL11405854 0.98 MEN1 (0.32) CA2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686250-A PRODUCING ANTIBODIES SPECIFIC TO LEVUGLANDIN CARRIER-PROTEIN BOUND PYRROLE ADDUCTS CASE WESTERN RESERVE UNIVERSITY (US) 1997-11-11 US disclosed
US-5329035-A Biosynthesis of prostaglandins TEIJIN LIMITED (JP) 1994-07-12 US disclosed
US-5194670-A Storage stability YUTAKA MIZUSHIMA, ASAHI GLASS COMPANY LTD. (JP) 1993-03-16 US disclosed
EP-0423697-A2 Emulsion of lipid containing a prostaglandin analogue MIZUSHIMA, Yutaka (JP) 1991-04-24 EP disclosed
EP-0178139-B1 PROCESS FOR PRODUCING 2,3-DISUBSTITUTED -4-SUBSTITUTED CYCLOPENTANONES, ENANTIOMORPHS, OR MIXTURES THEREOF TEIJIN LIMITED (JP) 1989-07-05 EP disclosed
US-4845282-A CHEMICAL INTERMEDIATES TEIJIN LIMITED (JP) 1989-07-04 US disclosed
EP-0102230-B1 NOVEL 6-NITROPROSTAGLANDIN DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF TEIJIN LIMITED (JP) 1987-04-29 EP disclosed
US-4649156-A ANTICOAGULANTS, HYPOTENSIVE, VASODILATORS, ANTITUMOR TEIJIN LIMITED (JP) 1987-03-10 US disclosed
EP-0079733-B1 PROCESS FOR PROSTAGLANDIN E1, PRODUCTION AND NOVEL DELTA 7-PROSTAGLANDINES E AND 7-HYDROXYPROSTAGLANDINS E TEIJIN LIMITED (JP) 1987-03-04 EP disclosed
EP-0178139-A2 Process for producing 2,3-disubstituted -4-substituted cyclopentanones, enantiomorphs, or mixtures thereof TEIJIN LIMITED (JP) 1986-04-16 EP disclosed
EP-0102230-A2 Novel 6-nitroprostaglandin derivatives, process for production thereof, and use thereof TEIJIN LIMITED (JP) 1984-03-07 EP disclosed
EP-0100900-A1 Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1984-02-22 EP disclosed
US-4423068-A (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties SYNTEX (U.S.A.) INC. (US) 1983-12-27 US disclosed
EP-0079733-A2 Process for prostaglandin E1, production and novel delta 7-prostaglandines E and 7-hydroxyprostaglandins E TEIJIN LIMITED (JP) 1983-05-25 EP disclosed
US-4272629-A Novel prostaglandin intermediates ALLEN & HANBURYS LIMITED (GB) 1981-06-09 US disclosed
US-4234720-A Prostaglandin derivatives ABBOTT LABORATORIES (US) 1980-11-18 US disclosed
US-4188331-A Prostaglandin derivatives ABBOTT LABORATORIES (US) 1980-02-12 US disclosed
US-4139717-A 1,3-Dicarbonyl compounds TEIJIN LIMITED (JP) 1979-02-13 US disclosed
US-4117014-A PROSTAGLANDIN DERIVATIVES ABBOTT LABORATORIES (US) 1978-09-26 US disclosed
US-4009196-A HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS TEIJIN LIMITED (JA) 1977-02-22 US disclosed