Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106389 | 0.96 | CA1 (0.52) | CA1POLBCA2CA7CA9 | |
| SCHEMBL10547943 | 0.88 | CA1 (0.50) | CA1POLBCA2CA7CA9 | |
| SCHEMBL8116441 | 0.82 | CA1 (0.55) | CA1POLBCA2CA7CA9 | |
| SCHEMBL8116438 | 0.82 | CA1 (0.55) | CA1POLBCA2CA7CA9 | |
| SCHEMBL9662857 | 0.81 | CA1 (0.54) | CA1POLBCA2CA7CA9 | |
| SCHEMBL7153591 | 0.80 | CA1 (0.76) | CA1POLBCA2CA7CA9 | |
| SCHEMBL4068078 | 0.78 | SIGMAR1 (0.53) | SIGMAR1TSHRMEN1KMT2A | |
| SCHEMBL8117102 | 0.78 | SIGMAR1 (0.41) | CA1POLBSIGMAR1MEN1KMT2A | |
| SCHEMBL8116821 | 0.78 | SIGMAR1 (0.41) | CA1POLBSIGMAR1MEN1KMT2A | |
| SCHEMBL8121598 | 0.77 | CA1 (0.50) | CA1POLBCA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614550-A | ANTICHOLESTEROL AGENTS OR ARTERIOSCLEROSIS AGENTS FOR HUMANS | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5534529-A | Substituted aromatic amides and ureas derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-09 | — | — | US | disclosed |