Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839095 | 0.91 | PREP (0.38) | L3MBTL1HTR2CKLK7KLK5PDK1 | |
| SCHEMBL8838990 | 0.84 | L3MBTL1 (0.44) | L3MBTL1HTR2CKLK7KLK5PREP | |
| SCHEMBL8839067 | 0.84 | L3MBTL1 (0.36) | L3MBTL1HTR2CKLK7KLK5PREP | |
| SCHEMBL8838999 | 0.83 | L3MBTL1 (0.37) | L3MBTL1HTR2CKLK7KLK5PREP | |
| SCHEMBL8839088 | 0.83 | L3MBTL1 (0.37) | L3MBTL1HTR2CKLK7KLK5PREP | |
| SCHEMBL9077430 | 0.81 | PREP (0.41) | L3MBTL1HTR2CKLK7KLK5PREP | |
| SCHEMBL8796249 | 0.81 | PREP (0.41) | L3MBTL1HTR2CKLK7KLK5PREP | |
| SCHEMBL9079150 | 0.80 | KLK7 (0.38) | L3MBTL1HTR2CKLK7KLK5PREP | |
| SCHEMBL9010721 | 0.79 | KLK7 (0.36) | L3MBTL1KLK7KLK5PREPAGTR2 | |
| SCHEMBL9230633 | 0.76 | L3MBTL1 (0.42) | L3MBTL1HTR2CKLK7KLK5PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684138-A | Asymmetrical reactive dyes containing two triazinyl radicals which are bridged via an aliphatic bridge member | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5639882-A | CHEMICAL INTERMEDIATES FOR FORMING VIRICIDES INHIBITING LENTIVIRUSES | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5637707-A | STEREOSELECTIVELY ADDING ORGANONETALLIC REAGENT BY NUCLEOPHILIC ADDITION TO KETONE COMPOUND | G. D. SEARLE & CO. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5601621-A | PRETREATING WITH SODIUM HYDROXIDE AND 2-OXO-1,3-OXAZOLIDINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5552532-A | Reactive dyes, processes for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0566556-B1 | 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds | SEARLE & CO (US) | 1996-07-03 | — | — | EP | disclosed |
| US-5530132-A | VIRICIDES, HIV VIRUS | G. D. SEARLE & CO. (US) | 1996-06-25 | — | — | US | disclosed |
| US-5523406-A | STEREOSPECIFIC ALKYLATION BY NUCLEOPHILIC ADDITION AT C-2 WITH A GRIGNARD REAGENT | G. D. SEARLE & CO. (US) | 1996-06-04 | — | — | US | disclosed |
| US-5350854-A | AIDS treatment | G. D. SEARLE & CO. (US) | 1994-09-27 | — | — | US | disclosed |
| US-5258518-A | Antiviral agents, anti-HIV activity | G. D. SEARLE & CO. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0566556-A1 | 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds | G.D. Searle & Co. (US) | 1993-10-20 | — | — | EP | disclosed |
| US-4693727-A | Process for dyeing synthetic polyamide materials with fibre-reactive anthraquinone dyes | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | disclosed |
| US-4652269-A | Process for the continuous trichromatic dyeing of synthetic polyamide materials: including a blue anthraquinone reactive dye | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |