SCHEMBL8839282

SCHEMBL8839282

CCCCCCCCCCC(=O)OCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.62
DNM1 Q05193 1/20 0.53
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
PAM P19021 2/20 0.49
NAAA Q02083 1/20 0.49
HTR2C P28335 1/20 0.47
TSHR P16473 1/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 2/20 0.45
ALDH1A1 P00352 1/20 0.45
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8839190 1.00 DGKA (0.62) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL8839110 1.00 DGKA (0.62) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL8839165 0.93 DGKA (0.52) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL6267406 0.88 DGKA (0.44) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL176417 0.88 DGKA (0.42) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL8839286 0.85 DGKA (0.65) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL8839367 0.85 DGKA (0.65) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL8839460 0.85 DGKA (0.65) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL4459130 0.84 DGKA (0.41) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25243121 0.80 DGKA (0.87) DGKADNM1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679821-A Process for preparing organosilicon compound TOAGOSEI CO., LTD. (JP) 1997-10-21 US disclosed