Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839367 | 1.00 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8839460 | 1.00 | DGKA (0.65) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL4358005 | 0.93 | DGKA (0.53) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL5159381 | 0.91 | DGKA (0.48) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL6271674 | 0.88 | DGKA (0.46) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL5164186 | 0.86 | ADRA2A (0.43) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8839110 | 0.85 | DGKA (0.62) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8839190 | 0.85 | DGKA (0.62) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8839282 | 0.85 | DGKA (0.62) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL25243121 | 0.82 | DGKA (0.87) | DGKADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679821-A | Process for preparing organosilicon compound | TOAGOSEI CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |