Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839945 | 0.86 | FFAR1 (0.53) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL5111304 | 0.84 | FFAR1 (0.58) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL7210573 | 0.84 | FFAR1 (0.52) | FFAR1PPARGPPARAMAOBHRH3 | |
| SCHEMBL5099205 | 0.83 | FFAR1 (0.60) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL4746580 | 0.82 | FFAR1 (0.56) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL4748088 | 0.82 | FFAR1 (0.59) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL7159209 | 0.82 | FFAR1 (0.56) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL13542481 | 0.81 | PPARG (0.62) | FFAR1PPARGPPARALMNA | |
| SCHEMBL4747685 | 0.81 | FFAR1 (0.52) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL8839962 | 0.79 | FFAR1 (0.50) | FFAR1PPARGPPARAHRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641796-A | PHENYL-OXAZOLYL-ALKYLOXY OR THIO-PHENYLALKYL TRIAZOLINE-3-ONE OR THIONE ANTIDIABETIC AGENT | ELI LILLY AND COMPANY (US) | 1997-06-24 | — | — | US | disclosed |