Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.69 |
| ▸ | MMP9 | P14780 | 4/20 | 0.69 |
| ▸ | MMP1 | P03956 | 2/20 | 0.69 |
| ▸ | MMP3 | P08254 | 2/20 | 0.69 |
| ▸ | MMP7 | P09237 | 2/20 | 0.69 |
| ▸ | MMP13 | P45452 | 2/20 | 0.69 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GRN | P28799 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062306 | 1.00 | MMP2 (0.69) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7066879 | 0.88 | MMP2 (0.69) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL1871538 | 0.87 | MMP2 (0.53) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL1879215 | 0.87 | MMP2 (0.53) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL11351046 | 0.87 | MMP9 (0.71) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7066619 | 0.87 | MMP9 (0.71) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL3969625 | 0.87 | MMP9 (0.71) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6561338 | 0.86 | MMP2 (0.70) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL5191083 | 0.86 | MMP2 (0.70) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL15251807 | 0.86 | MMP2 (0.70) | MMP2MMP9MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650428-A | THROMBOXANE A2 ANTAGONISM | NKK CORPORATION (JP) | 1997-07-22 | — | — | US | disclosed |