Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19814620 | 0.98 | TTR (0.46) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL30824456 | 0.86 | ROCK2 (0.47) | KDM4EALDH1A1KMOHDAC3HDAC4 | |
| SCHEMBL29541937 | 0.85 | HDAC3 (0.41) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL30824454 | 0.85 | ROCK2 (0.46) | KDM4EALDH1A1KMOHDAC3HDAC4 | |
| Lithium Ion SCHEMBL29939266 | 0.85 | HDAC3 (0.41) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL8840310 | 0.82 | KDM4E (0.54) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL25234053 | 0.79 | MAPT (0.46) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL8840334 | 0.77 | CSNK2A2 (0.56) | KDM4EMEN1LMNAKMT2AHDAC1 | |
| SCHEMBL27153036 | 0.75 | KMO (0.49) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL22617533 | 0.75 | KDM4E (0.58) | KDM4EMEN1KMT2AKMOHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591695-A | Herbicidal [1,3,4]oxadiazoles and thiadiazoles | AMERICAN CYANAMID CO. (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0726263-A2 | Herbicidal (1,3,4)oxadiazoles and thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |