Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840429 | 1.00 | HTR1A (0.33) | HTR1AADRA1DADRA1AADRA1BGRM2 | |
| SCHEMBL8840507 | 0.86 | GRM2 (0.39) | HTR1AADRA1DADRA1AADRA1BGRM2 | |
| SCHEMBL8840497 | 0.86 | GRM2 (0.39) | HTR1AADRA1DADRA1AADRA1BGRM2 | |
| SCHEMBL8840573 | 0.84 | FGFR2 (0.37) | ALDH1A1 | |
| SCHEMBL8840570 | 0.84 | FGFR2 (0.37) | ALDH1A1 | |
| SCHEMBL8705767 | 0.83 | HTR1A (0.38) | HTR1AADRA1DADRA1AADRA1BGRM2 | |
| SCHEMBL8705766 | 0.83 | HTR1A (0.38) | HTR1AADRA1DADRA1AADRA1BGRM2 | |
| SCHEMBL8840433 | 0.80 | PRMT5 (0.36) | HTR1AADRA1DADRA1AADRA1BGRM2 | |
| SCHEMBL8840426 | 0.80 | PRMT5 (0.36) | HTR1AADRA1DADRA1AADRA1BGRM2 | |
| SCHEMBL8706057 | 0.77 | MGLL (0.39) | HTR1AADRA1DADRA1AADRA1BGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |