Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840396 | 0.91 | MEN1 (0.33) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8416637 | 0.83 | MEN1 (0.36) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8840576 | 0.80 | TRPM8 (0.32) | JAK2JAK1JAK3 | |
| SCHEMBL8840520 | 0.79 | NPC1 (0.41) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8415221 | 0.79 | TRPM8 (0.35) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8705045 | 0.74 | MEN1 (0.35) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8840468 | 0.74 | JAK2 (0.33) | MEN1MAPTKMT2ASMN1; SMN2JAK2 | |
| SCHEMBL8417992 | 0.73 | JAK2 (0.36) | MEN1MAPTKMT2ASMN1; SMN2JAK2 | |
| SCHEMBL8840494 | 0.70 | KMT2A (0.34) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8840537 | 0.70 | JAK2 (0.31) | JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |