SCHEMBL8840550

SCHEMBL8840550

C=CCOCc1nccc(N(OCc2ccccc2)[C@H]2CC[C@@H](C(C)(C)C)CC2)c1OC

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
NPBWR1 P48145 1/20 0.30
KMT2A Q03164 1/20 0.30
MCHR1 Q99705 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840430 0.89 KMT2A (0.33) NPBWR1KMT2AMCHR1
SCHEMBL8840443 0.88 L3MBTL1 (0.33) L3MBTL1
SCHEMBL8840494 0.84 KMT2A (0.34) NPBWR1KMT2AMCHR1
SCHEMBL8840521 0.78 KMT2A (0.33) NPBWR1KMT2AMCHR1
SCHEMBL8840493 0.77 AVPR1A (0.31)
SCHEMBL8840417 0.76 GRM2 (0.34)
SCHEMBL27449186 0.76 KMT2A (0.33) L3MBTL1NPBWR1KMT2AMCHR1
SCHEMBL8840555 0.75 L3MBTL1 (0.34) L3MBTL1
SCHEMBL9033980 0.75
SCHEMBL9035774 0.74 KDM4E (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed
EP-0719255-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007890-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed