SCHEMBL8840860

SCHEMBL8840860

COc1cc2c(nc1O)c1cc(OC)c(OC)nc1c1cc(OC)c(OC)nc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
NQO2 P16083 3/20 0.33
KDM4E B2RXH2 2/20 0.33
PDE4A P27815 1/20 0.33
PDE4D Q08499 1/20 0.33
STING1 Q86WV6 1/20 0.33
GPR35 Q9HC97 1/20 0.33
MAPT P10636 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
RAC1 P63000 2/20 0.32
POLB P06746 2/20 0.32
GAA P10253 2/20 0.32
TRPA1 O75762 1/20 0.31
ABL1 P00519 1/20 0.31
PKM P14618 1/20 0.31
APEX1 P27695 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3878857 0.79 ALDH1A1 (0.46) KMT2AMEN1NQO2KDM4EMAPT
SCHEMBL14280967 0.73 TLR8 (0.50) KMT2AMEN1NQO2KDM4EMAPT
SCHEMBL118146 0.73 CYP3A4 (0.44) KMT2AMEN1NQO2KDM4EPDE4A
SCHEMBL14316197 0.71 KDM4E (0.39) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL28695578 0.70 PDE4A (0.40) KMT2AMEN1KDM4EPDE4APDE4D
SCHEMBL30466587 0.70 RET (0.39) KMT2AMEN1TRPA1
SCHEMBL21198876 0.70 RET (0.39) KMT2AMEN1TRPA1
SCHEMBL30103982 0.70 PDE4A (0.40) KMT2AMEN1KDM4EPDE4APDE4D
SCHEMBL21199560 0.66 PDGFRB (0.44) NQO2POLBABL1
SCHEMBL29812357 0.66 PDGFRB (0.44) NQO2POLBABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5637669-A THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-06-10 US disclosed
EP-0670856-A1 THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP disclosed
WO-1994012556-A2 THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO disclosed