SCHEMBL118146

SCHEMBL118146

COc1cc(OC)c(O)nc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 3/20 0.44
MAOB P27338 1/20 0.41
NQO2 P16083 2/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
CA1 P00915 3/20 0.39
TP53 P04637 3/20 0.39
CA2 P00918 2/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 3/20 0.38
CA12 O43570 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA3 P07451 1/20 0.38
PKM P14618 1/20 0.38
CA4 P22748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20704256 0.75 NPSR1 (0.47) ALDH1A1MAPTNQO2LMNAALOX5
SCHEMBL1258372 0.74 NQO2 (0.58) CYP3A4ALDH1A1MAPTNQO2PDE4A
SCHEMBL8840860 0.73 KMT2A (0.34) CYP3A4ALDH1A1MAPTNQO2PDE4A
SCHEMBL1276533 0.71 CYP3A4 (0.59) CYP3A4ALDH1A1MAPTNQO2PDE4A
SCHEMBL6608419 0.70 NQO2 (0.43) CYP3A4ALDH1A1MAPTMAOBNQO2
SCHEMBL2148581 0.70 ALDH1A1 (0.38) CYP3A4ALDH1A1MAPTMAOBNQO2
SCHEMBL31366357 0.70 ALDH1A1 (0.38) CYP3A4ALDH1A1MAPTMAOBNQO2
SCHEMBL3169433 0.69 FTO (0.40) CYP3A4ALDH1A1MAPTNQO2CA1
SCHEMBL22042471 0.69 ALDH1A1 (0.40) CYP3A4ALDH1A1MAPTMAOBCA1
SCHEMBL18814147 0.69 ACHE (0.43) CYP3A4ALDH1A1MAPTMAOBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242864-A1 DISCOLORING COMPOSITION FOR KERATIN FIBERS DYED WITH BLEACH-STABLE DIRECT DYES KAO CORPORATION (JP) 2025-11-27 WO claimed
EP-4408377-B1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KAO CORP (JP) 2025-10-08 EP claimed
US-20240390243-A1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KAO CORPORATION (JP) 2024-11-28 US claimed
US-20240390244-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE SALT KAO CORPORATION (JP) 2024-11-28 US claimed
US-20240382394-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE AND AMINE SALT KAO CORPORATION (JP) 2024-11-21 US claimed
EP-4408378-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE SALT Kao Corporation (JP) 2024-08-07 EP claimed
EP-4408377-A2 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES Kao Corporation (JP) 2024-08-07 EP claimed
CN-118119370-A Composition comprising an oxidation dye and a direct dye 花王株式会社 2024-05-31 CN claimed
CN-118055753-A Composition comprising an oxidation dye and an amine salt 花王株式会社 2024-05-17 CN claimed
CN-118043021-A Composition comprising oxidation dye salts 花王株式会社 2024-05-14 CN claimed
EP-1250909-B1 Hair dye composition KPSS KAO GMBH (DE) 2004-10-06 EP claimed
EP-1250911-B1 Hair dye composition KPSS KAO GMBH (DE) 2004-09-22 EP claimed
EP-1250912-B1 Hair dye composition KPSS KAO GMBH (DE) 2004-09-15 EP claimed
EP-1297818-A2 Hair dye KPSS-Kao Professional Salon Services GmbH (DE) 2003-04-02 EP claimed
EP-1250910-A1 Hair dye composition GOLDWELL GmbH (DE) 2002-10-23 EP claimed
EP-1250909-A1 Hair dye composition GOLDWELL GmbH (DE) 2002-10-23 EP claimed
EP-1250912-A1 Hair dye composition GOLDWELL GmbH (DE) 2002-10-23 EP claimed
EP-1250908-A2 Hair dye GOLDWELL GmbH (DE) 2002-10-23 EP claimed
EP-1250911-A1 Hair dye composition GOLDWELL GmbH (DE) 2002-10-23 EP claimed
WO-2002026200-A1 OXIDATION DYES WITH 2-AMINO-5-METHYLPHENOL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-04-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240390243-A1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KRT18, CYBA, CYBB CYP3A4 394/4885ALDH1A1 372/4885MAPT 856/4885
US-20240390244-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE SALT CS, SDHA, MDH2 CYP3A4 2536/4885ALDH1A1 231/4885MAPT 1203/4885
US-20240382394-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE AND AMINE SALT KRT18, AOC1, MUC1 CYP3A4 2538/4885ALDH1A1 222/4885MAPT 785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.