Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580906 | 0.89 | CA1 (0.55) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL18624702 | 0.86 | PTPN1 (0.51) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL18098085 | 0.86 | PTPN1 (0.51) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL18686393 | 0.86 | CA1 (0.61) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL21811067 | 0.84 | PTPN1 (0.42) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL19360285 | 0.84 | PTPN1 (0.59) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL16639593 | 0.84 | PTPN1 (0.59) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL6703974 | 0.84 | ALDH1A1 (0.52) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL13309714 | 0.83 | ALDH1A1 (0.50) | CA1CA2PTPN1PTGS1PTGS2 | |
| SCHEMBL14216960 | 0.82 | CA1 (0.48) | CA1CA2PTPN1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637669-A | THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-06-10 | — | — | US | disclosed |