Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840950 | 0.93 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8840984 | 0.88 | LMNA (0.40) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8841006 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTHRH3 | |
| SCHEMBL8840966 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8840955 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8840991 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8841015 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8840968 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10366783 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9738308 | 0.76 | LMNA (0.38) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597918-A | ANXIOLYTIC AGENTS, SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-28 | — | — | US | disclosed |