Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022422 | 0.79 | MCL1 (0.60) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL26602375 | 0.74 | HIF1A (0.64) | KDM4EHIF1A | |
| SCHEMBL8305401 | 0.74 | CA12 (0.53) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL8841212 | 0.71 | ALDH1A1 (0.46) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL7032769 | 0.70 | KCNH2 (0.61) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL30608265 | 0.67 | NPC1 (0.61) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL17786550 | 0.67 | CSNK2A2 (0.55) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL1065472 | 0.67 | MCL1 (0.71) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL2785581 | 0.67 | NPC1 (0.58) | MAPTKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL19661814 | 0.66 | KCNH2 (0.60) | MAPTKDM4EKMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622989-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | claimed |