Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065472 | 0.86 | MCL1 (0.71) | KCNH2NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL19661814 | 0.84 | KCNH2 (0.60) | KCNH2NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL29539987 | 0.84 | KCNH2 (0.60) | KCNH2NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL11545219 | 0.83 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2GAAMCL1 | |
| SCHEMBL11686876 | 0.83 | MCL1 (0.77) | KCNH2RAB9ASMN1; SMN2PKMMCL1 | |
| SCHEMBL11095152 | 0.81 | PKM (0.64) | KCNH2NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL6238414 | 0.80 | KCNH2 (0.63) | KCNH2NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL30608265 | 0.79 | NPC1 (0.61) | KCNH2NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL19661983 | 0.79 | KCNH2 (0.66) | KCNH2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL114250 | 0.78 | KMT2A (0.60) | KCNH2NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926332-B2 | Dihydro-oxazinobenzodiazepine compounds, a process for their preparation and pharmaceutical compositions containing them | EGIS GYOGYSZERGYAR ZRT. (HU) | 2018-03-27 | — | — | US | disclosed |
| US-20170002020-A1 | NEW DIHYDRO-OXAZINOBENZODIAZEPINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM | EGIS GYOGYSZERGYAR ZRT. (HU) | 2017-01-05 | — | — | US | disclosed |
| EP-0826764-B1 | Perfuming compositions comprising substituted 2-acetylbenzofuranes | HAARMANN & REIMER GMBH (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-5972878-A | A PERFUME OIL FOR PERFUMING COSMETIC COMPOSITIONS, CLEANING COMPOSITIONS, DETERGENT COMPOSITIONS, SOFTENER COMPOSITIONS, DISINFECTANT COMPOSITIONS, TEXTILE TREATMENT COMPOSITIONS AND PERFUME COMPOSITIONS | HAARMANN & REIMER GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0826764-A2 | Use of substituted 2-acetylbenzofuranes as perfuming agents | HAARMANN & REIMER GMBH (DE) | 1998-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002020-A1 | NEW DIHYDRO-OXAZINOBENZODIAZEPINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM | GABRB2, GABRB3, GABRA5 | KCNH2 564/4885NPC1 2358/4885RAB9A 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.