Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338213 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL29743769 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL20298733 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL4054356 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL1448259 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL19357885 | 0.81 | CA1 (0.49) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL11317378 | 0.81 | CA1 (0.56) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL5971372 | 0.81 | AKR1B1 (0.52) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL25287029 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1CYP3A4ALOX15 | |
| SCHEMBL7589858 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTTDP1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616798-A | 2,2',4,4'6,6'-HEXAAMIDO-3,3',5,5'-TETRAIODOBIPHENYLS; RADIOLOGY | GUERBET S.A. (FR) | 1997-04-01 | — | — | US | disclosed |