Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28562586 | 0.81 | PARP1 (0.43) | KMT2AMAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL23727525 | 0.73 | POLB (0.41) | KMT2AMAPK1MAPTCYP1A2LMNA | |
| SCHEMBL7878088 | 0.72 | TSHR (0.66) | KMT2AMAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL30639225 | 0.72 | TSHR (0.66) | KMT2AMAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL27608072 | 0.71 | GAA (0.58) | KMT2AMAPK1MAPTLMNAKDM4E | |
| SCHEMBL4615959 | 0.70 | TSHR (0.53) | KMT2AMAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29367154 | 0.70 | KMT2A (0.43) | KMT2AMAPK1MAPTCYP1A2LMNA | |
| SCHEMBL25205865 | 0.70 | KMT2A (0.43) | KMT2AMAPK1MAPTCYP1A2LMNA | |
| SCHEMBL1920554 | 0.69 | ALDH1A1 (0.43) | KMT2AMAPK1MAPTLMNAKDM4E | |
| SCHEMBL3051294 | 0.69 | GAA (0.49) | KMT2AMAPK1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599772-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5565411-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5554579-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1996-09-10 | — | — | US | disclosed |