Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | PAM | P19021 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890414 | 0.84 | MCL1 (0.43) | MCL1TDP1ADRA2AADRA1AMAPT | |
| SCHEMBL11585251 | 0.81 | MCL1 (0.50) | MCL1LMNAL3MBTL1TSHRADRA2A | |
| SCHEMBL23231149 | 0.79 | MCL1 (0.40) | MCL1LMNATDP1ALDH1A1MAPT | |
| SCHEMBL20368988 | 0.79 | NAAA (0.41) | MCL1LMNATSHRTDP1ALDH1A1 | |
| SCHEMBL8841248 | 0.79 | TSHR (0.46) | MCL1LMNATSHRADRA2AADRA1A | |
| SCHEMBL10835416 | 0.78 | CYP1A2 (0.42) | MCL1LMNAL3MBTL1TSHRADRA2A | |
| SCHEMBL3785372 | 0.77 | MCL1 (0.39) | MCL1TSHRALDH1A1 | |
| SCHEMBL10396864 | 0.77 | MCL1 (0.39) | MCL1TDP1ALDH1A1 | |
| SCHEMBL13557224 | 0.77 | MCL1 (0.39) | MCL1TSHRALDH1A1 | |
| SCHEMBL31678679 | 0.77 | NAAA (0.45) | MCL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652371-A | 3-imino-3-alkoxy-propionic acid lactates and their tautomeric acrylic acid lactates | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |