Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835416 | 0.82 | CYP1A2 (0.42) | TSHRMCL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10835475 | 0.81 | MCL1 (0.43) | TSHRMCL1ALDH1A1HPGDKMT2A | |
| SCHEMBL180857 | 0.80 | — | — | |
| SCHEMBL6890414 | 0.80 | MCL1 (0.43) | MCL1KMT2AMEN1MAPTADRA2A | |
| SCHEMBL10834424 | 0.79 | DGKA (0.48) | TSHRALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL755188 | 0.79 | TSHR (0.38) | TSHRMCL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8841240 | 0.79 | MMP2 (0.40) | TSHRMCL1ALDH1A1LMNAMAPT | |
| Methane SCHEMBL28190838 | 0.78 | MCL1 (0.48) | TSHRMCL1ALDH1A1HPGDKMT2A | |
| SCHEMBL29285367 | 0.78 | — | — | |
| Methane SCHEMBL28190144 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652371-A | 3-imino-3-alkoxy-propionic acid lactates and their tautomeric acrylic acid lactates | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| US-4582648-A | QUICK-SETTING;ODORLESS | KABUSHIKI KAISHA ALPHA GIKEN (JP) | 1986-04-15 | — | — | US | disclosed |
| EP-0127855-A1 | Novel alpha-cyanoacrylate compound, method of preparing same and adhesive comprising same | Kabushiki Kaisha Alpha Giken (JP) | 1984-12-12 | — | — | EP | disclosed |