Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740293 | 0.89 | — | — | |
| SCHEMBL8740108 | 0.65 | NR1I2 (0.44) | POLBMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8740109 | 0.65 | NR1I2 (0.44) | POLBMAPTSMN1; SMN2ALDH1A1KMT2A | |
| Trimethyl Phosphate SCHEMBL28722575 | 0.61 | ALOX15 (0.36) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27692038 | 0.60 | — | — | |
| SCHEMBL11340495 | 0.60 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL28062661 | 0.60 | ESR2 (0.39) | SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL328840 | 0.59 | ALDH1A1 (0.30) | ALDH1A1 | |
| Formic Acid Methyl Ester SCHEMBL16044022 | 0.59 | ALDH1A1 (0.36) | SMN1; SMN2ERN1ALDH1A1 | |
| SCHEMBL11456405 | 0.58 | MAPT (0.52) | POLBMAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703263-A | USEFUL AS ANTIBIOTICS AND/OR AS INTERMEDIATES IN THE PREPARATION OF PHOSPHORUS-CONTAINING ANALOGS OF PEPTIDES | MONSANTO COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5321153-A | Asymetric hydrogenation | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | disclosed |