Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959551 | 0.79 | TDP1 (0.59) | STING1TDP1EPHX1EPHX2KMT2A | |
| SCHEMBL8843536 | 0.78 | HDAC3 (0.43) | TDP1CYP1A2ALPLCYP2C9TSHR | |
| SCHEMBL21611670 | 0.77 | STING1 (0.54) | STING1TDP1EPHX1TSHRSMN1; SMN2 | |
| SCHEMBL15656106 | 0.74 | MEN1 (0.53) | STING1TDP1EPHX1TSHRSMN1; SMN2 | |
| SCHEMBL28239404 | 0.74 | GAA (0.55) | STING1TDP1EPHX1TSHRSMN1; SMN2 | |
| SCHEMBL8523258 | 0.73 | MEN1 (0.62) | SMN1; SMN2LMNAGAAEPHX2MEN1 | |
| SCHEMBL4811573 | 0.73 | TSHR (0.41) | CYP1A2CYP2C9TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL26699105 | 0.73 | STING1 (0.48) | STING1TDP1EPHX1TSHRSMN1; SMN2 | |
| SCHEMBL16742500 | 0.72 | CYP1A2 (0.53) | TDP1CYP1A2ALPLCYP2C9TSHR | |
| SCHEMBL23782476 | 0.72 | GAA (0.53) | TDP1GAAEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |