Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843465 | 0.93 | ALDH1A1 (0.40) | HDAC3ALDH1A1KMT2AHDAC2MEN1 | |
| SCHEMBL16742500 | 0.78 | CYP1A2 (0.53) | ALDH1A1TDP1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL8843835 | 0.78 | ALDH1A1 (0.66) | HDAC3ALDH1A1KMT2AHDAC2HDAC8 | |
| SCHEMBL8843218 | 0.78 | STING1 (0.39) | TDP1KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL8523258 | 0.77 | MEN1 (0.62) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11293971 | 0.74 | HPGD (0.51) | ALDH1A1TDP1KMT2ACYP2C19MEN1 | |
| SCHEMBL18956292 | 0.74 | TRPV1 (0.56) | HDAC3ALDH1A1KMT2AL3MBTL1HDAC2 | |
| SCHEMBL23782476 | 0.73 | GAA (0.53) | ALDH1A1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL8044468 | 0.73 | TDP1 (0.46) | HDAC3ALDH1A1TDP1KMT2ACYP3A4 | |
| SCHEMBL18956278 | 0.73 | MEN1 (0.52) | KMT2AHDAC2MEN1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |