Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.39 |
| ▸ | MC1R | Q01726 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843470 | 0.94 | MC5R (0.40) | MC5RMC1R | |
| SCHEMBL9706212 | 0.79 | EPHX1 (0.51) | ELANEPSMB5EPHX1MEP1B | |
| SCHEMBL8843830 | 0.79 | EPHX1 (0.51) | ELANEPSMB5EPHX1MEP1B | |
| SCHEMBL19450068 | 0.74 | POLB (0.51) | PSMB5 | |
| SCHEMBL8843372 | 0.73 | DAGLA (0.41) | PSMB5 | |
| SCHEMBL5653982 | 0.73 | PDCD1 (0.49) | EPHX1 | |
| SCHEMBL26523520 | 0.73 | CYP1A2 (0.47) | EPHX1 | |
| SCHEMBL5653973 | 0.73 | PDCD1 (0.49) | EPHX1 | |
| SCHEMBL1576808 | 0.73 | PDCD1 (0.49) | EPHX1 | |
| SCHEMBL18375339 | 0.72 | ACE (0.51) | PSMB5MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |