Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843830 | 1.00 | EPHX1 (0.51) | EPHX1MEP1BPSMB5SIGMAR1ANPEP | |
| SCHEMBL18375339 | 0.92 | ACE (0.51) | MEP1BPSMB5HPGDSSLC7A5 | |
| SCHEMBL20362252 | 0.92 | ACE (0.51) | MEP1BPSMB5HPGDSSLC7A5 | |
| SCHEMBL11826525 | 0.86 | SIGMAR1 (0.55) | MEP1BPSMB5SIGMAR1ANPEPATM | |
| SCHEMBL5597677 | 0.86 | EPHX1 (0.51) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL1576808 | 0.86 | PDCD1 (0.49) | EPHX1 | |
| SCHEMBL26523520 | 0.86 | CYP1A2 (0.47) | EPHX1 | |
| SCHEMBL5597679 | 0.86 | EPHX1 (0.51) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL5653982 | 0.86 | PDCD1 (0.49) | EPHX1 | |
| SCHEMBL5653973 | 0.86 | PDCD1 (0.49) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1278791-A | Process for the preparation of azacyclkylalkanoyl pseudotetrapeptides | HOECHST PHARMA (US) | 2001-01-03 | — | — | CN | disclosed |
| WO-1992011232-A1 | CHELATING AGENTS | NYCOMED IMAGING AS (NO) | 1992-07-09 | — | — | WO | disclosed |