Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843065 | 0.79 | ALDH1A1 (0.40) | DAGLATRPV1ALDH1A1PSMB5TACR1 | |
| SCHEMBL9706212 | 0.78 | EPHX1 (0.51) | PSMB5 | |
| SCHEMBL8843830 | 0.78 | EPHX1 (0.51) | PSMB5 | |
| SCHEMBL8843375 | 0.74 | HDAC6 (0.45) | HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL8843541 | 0.73 | MC5R (0.39) | PSMB5 | |
| SCHEMBL19450068 | 0.73 | POLB (0.51) | PSMB5 | |
| Hydrochloric Acid SCHEMBL8844340 | 0.73 | SIRT2 (0.46) | LMNA | |
| SCHEMBL4849385 | 0.72 | HDAC1 (0.49) | HDAC1HDAC6ALDH1A1LMNAHTT | |
| SCHEMBL5653982 | 0.72 | PDCD1 (0.49) | ALDH1A1 | |
| SCHEMBL1576808 | 0.72 | PDCD1 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |