Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | GLUL | P15104 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744581 | 1.00 | SLC7A5 (0.42) | SLC7A5GLULGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4093592 | 0.80 | FOLH1 (0.40) | — | |
| Water SCHEMBL11413207 | 0.77 | FOLH1 (0.39) | — | |
| SCHEMBL153628 | 0.74 | SLC7A5 (0.42) | SLC7A5GLULGRIN2DGRIN3BGRIN1 | |
| SCHEMBL153629 | 0.74 | SLC7A5 (0.42) | SLC7A5GLULGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28029009 | 0.74 | SLC7A5 (0.42) | SLC7A5GLULGRIN2DGRIN3BGRIN1 | |
| SCHEMBL180909 | 0.72 | FOLH1 (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Water SCHEMBL22390098 | 0.72 | SLC7A5 (0.40) | SLC7A5GLULGRIN2DGRIN3BGRIN1 | |
| Phosphoric Acid SCHEMBL15322351 | 0.72 | SLC7A5 (0.40) | SLC7A5GLULGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8973660 | 0.72 | SLC7A5 (0.52) | SLC7A5GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |
| CN-1088931-A | New phosphonosuccinic acid derivatives and preparation method thereof and the pharmaceutical composition that contains these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-07-06 | — | — | CN | disclosed |