Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843865 | 0.96 | F2 (0.49) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL340393 | 0.80 | SMN1; SMN2 (0.72) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8843744 | 0.78 | ALDH1A1 (0.65) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL8843661 | 0.78 | ALDH1A1 (0.52) | HPGDKDM4EALDH1A1ABCB1MEN1 | |
| SCHEMBL11730888 | 0.76 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8843736 | 0.75 | TSHR (0.55) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1609793 | 0.75 | F2 (0.53) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8850238 | 0.75 | MAPT (0.53) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3809016 | 0.74 | F2 (0.52) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| Hydrogen Sulfide SCHEMBL3809014 | 0.74 | F2 (0.52) | HPGDSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |