Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843764 | 0.96 | HPGD (0.53) | F2PRKCZHPGDKDM4EALDH1A1 | |
| SCHEMBL8843661 | 0.78 | ALDH1A1 (0.52) | HPGDKDM4EALDH1A1MEN1GAA | |
| SCHEMBL8843744 | 0.78 | ALDH1A1 (0.65) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11730888 | 0.76 | NPC1 (0.50) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8843771 | 0.75 | PDE4A (0.52) | SMPD1HDAC1HDAC8HDAC6HPGD | |
| SCHEMBL1609793 | 0.75 | F2 (0.53) | F2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL340393 | 0.75 | SMN1; SMN2 (0.72) | SMPD1HDAC1HDAC8HDAC6HPGD | |
| Hydrogen Sulfide SCHEMBL3809014 | 0.74 | F2 (0.52) | F2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL3809016 | 0.74 | F2 (0.52) | F2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL8843535 | 0.74 | PDE4A (0.63) | SMPD1HDAC1HDAC8HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |