Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242133 | 0.84 | PPARG (0.45) | PPARGALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL12431888 | 0.80 | HTR1A (0.50) | ALDH1A1KDM4EGAAMGAMSI | |
| SCHEMBL10429223 | 0.79 | KDM4E (0.48) | PPARGALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL12585085 | 0.77 | MAPK1 (0.51) | ALDH1A1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL27998563 | 0.77 | MAOB (0.59) | PPARGALDH1A1GAAMGAMSI | |
| SCHEMBL10925538 | 0.77 | HTR1A (0.50) | ALDH1A1KDM4ELMNAGAAMGAM | |
| SCHEMBL16707013 | 0.76 | ALDH1A1 (0.59) | PPARGALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL5237170 | 0.75 | APP (0.56) | ALDH1A1KDM4EGAAMGAMSI | |
| SCHEMBL5234365 | 0.75 | HTR1A (0.49) | ALDH1A1KDM4EGAAMGAMSI | |
| SCHEMBL8862695 | 0.75 | HTR1A (0.49) | ALDH1A1KDM4EGAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |