SCHEMBL8844007

SCHEMBL8844007

NC(=O)C1C2CC(C(Br)C2Br)C1C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11120680 0.78 NAAA (0.34)
SCHEMBL13216614 0.76 MAPK1 (0.55) MAPK1POLBTDP1
SCHEMBL3025318 0.76 MAPK1 (0.55) MAPK1POLBTDP1
SCHEMBL19015220 0.70
SCHEMBL26699411 0.68 EPHX1 (0.34) POLBTDP1
SCHEMBL19004703 0.68
SCHEMBL13346525 0.67 POLB (0.35) POLBTDP1
SCHEMBL4757873 0.66 MAPK1 (0.46) MAPK1POLBTDP1
SCHEMBL15232945 0.65 GLI1 (0.32) TDP1
SCHEMBL30107310 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5626912-A FORMING FABRIC USED IN CARPETS, RUGS AND UPHOLSTERY DSM N.V. (NL) 1997-05-06 US disclosed