Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 3/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22273540 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL4137685 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL8146945 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL27698377 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL30578035 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL8435134 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL21919739 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL21319262 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL627617 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL28156051 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |